Tylenol 350 mg Suppository 10 Pcs pain reliever is an analgesic and antipyretic that reduces fever. Using water or water-based lubricants to lubricate the tip of the suppository. Insert in the rectal opening the grained tip of the suppository. 6-9 year olds: 1 mg suppositories taken, 2-3 times a day. For 9-12 years: 1 350 mg 3-4 times daily suppository.